Background information
T Cell TransAct™ consists of a colloidal polymeric nanomatrix conjugated to humanized CD3 and CD28 agonists providing primary and co-stimulatory signals for an optimized and efficient T cell activation and expansion. The nanoscale structure of T Cell TransAct™ allows sterile filtration and excess reagent can be removed by centrifugation with following conventional supernatant replacement or simply by medium wash.
Polyclonal T cell expansion can be used when increased numbers of effector cells are required without the use of feeder cells or antigens, or when T cells are activated to enable gene modification.
